PhD positions available within the field of Disease Interception
Deadline: 23 February 2021
The Innovative Training Network (ITN) “INTERCEPT-MDS - Exploring cell-to-cell heterogeneity and exploiting epigenetic regulation for the interception of myeloid disease cells" is recruiting 12 highly motivated PhD candidates within the emerging field of disease interception. The offered positions are available with a duration of 36 months. The fellowships are funded as part of theMarie Skłodowska-Curie Actions (MSCA) Innovative Training Networks under the European Commission’s Horizon 2020 programme.
One project is hosted by the Institut national de la sante et de la recherche medicale (INSERM), France:
Phenotypic heterogeneity of myelodysplastic cells and influence of epigenetic therapies. The PhD candidate will report, for the first time at the single cell level, the evolution of the transcriptome of leukaemic and nonleukaemic cells upon treatment with hypomethylating agents and IDH inhibitors. This will allow them to compare for the first time the channelling of genetic and phenotypic heterogeneity driven by different epigenetic therapies.